
Centre of Aging in Musculoskeletal Degeneration & Regeneration
The Centre is funded by the Research Grants Council, Hong Kong SAR, Areas of Excellence (AoE) Scheme (AoE/M-402/20: Aging, Skeletal Degeneration and Regeneration).
This project addresses the challenges of an aging global population, particularly in Hong Kong, where the elderly population is projected to rise from 15% in 2014 to 36% by 2064. This demographic shift is accompanied by a high incidence of age-associated osteoporosis and bone fractures, which occur globally at a rate of one every three seconds, imposing significant socio-economic and financial burdens.
Our Mission
To facilitate the clinical translation of innovative treatments for musculoskeletal disorders associated with aging. It focuses on multidisciplinary research to advance skeletal regeneration in the context of bone metabolic disorders and fragility injuries, with a specific interest in bioactive and biodegradable implant materials for temporal fixation and skeletal regeneration.
FROM BENCH TO BEDSIDE: A Paradigm for Translation of Class III Orthopaedic Implants
Sub-Projects
The “Aging, Skeletal Degeneration and Regeneration” program encompasses nine interconnected sub-projects that span fundamental biology, biomaterials innovation, degenerative disease mechanisms, and translational sciences.
Together, they form a comprehensive research framework aimed at understanding age-related musculoskeletal decline and advancing next-generation strategies for skeletal repair, regeneration, and clinical implementation.

























