top of page
主页背景_页面_2.jpg

Centre of Aging in Musculoskeletal Degeneration & Regeneration

The Centre is funded by the Research Grants Council, Hong Kong SAR, Areas of Excellence (AoE) Scheme (AoE/M-402/20: Aging, Skeletal Degeneration and Regeneration).

 

This project addresses the challenges of an aging global population, particularly in Hong Kong, where the elderly population is projected to rise from 15% in 2014 to 36% by 2064. This demographic shift is accompanied by a high incidence of age-associated osteoporosis and bone fractures, which occur globally at a rate of one every three seconds, imposing significant socio-economic and financial burdens.

​​

Our Mission

To facilitate the clinical translation of innovative treatments for musculoskeletal disorders associated with aging. It focuses on multidisciplinary research to advance skeletal regeneration in the context of bone metabolic disorders and fragility injuries, with a specific interest in bioactive and biodegradable implant materials for temporal fixation and skeletal regeneration.

FROM BENCH TO BEDSIDE: A Paradigm for Translation of Class III Orthopaedic Implants

Our Services

Sub-Projects

The “Aging, Skeletal Degeneration and Regeneration” program encompasses nine interconnected sub-projects that span fundamental biology, biomaterials innovation, degenerative disease mechanisms, and translational sciences.

 

Together, these sub-projects form a comprehensive research framework aimed at understanding age-related musculoskeletal decline and advancing next-generation strategies for skeletal repair, regeneration, and clinical implementation.

Age‑Related Musculoskeletal Degeneration

​Research addressing the mechanisms and progression of musculoskeletal decline associated with aging, with the goal of preserving long-term function and mobility.

Fracture Healing & Bone Regeneration

Studies focusing on the biological and biomechanical processes of fracture repair and strategies to enhance bone regeneration.

Cellular & Molecular Mechanisms

Investigations that elucidate the cellular behaviours and molecular pathways underlying musculoskeletal development, pathology, and repair.

Biomaterials & Implant Design

Work exploring advanced biomaterials and implant engineering to improve safety, performance, and integration in orthopaedic applications.

Cartilage Repair & Osteoarthritis

Research examining cartilage injury, degenerative joint disease, and interventions aimed at restoring joint structure and function.

Spine & Intervertebral Disc Regeneration

Studies on spinal disorders and disc degeneration, with an emphasis on therapeutic strategies to restore structural integrity and biomechanical function.

Neuro‑
Musculoskeletal Interface

Investigations focusing on the interactions between the nervous system and musculoskeletal tissues, particularly in injury, regeneration, and functional restoration.

Guidelines & Standards

Literature that informs the development of musculoskeletal-related guidelines and standards derived from this project’s research outcomes.

Clinical Translation & Regulatory Science

Work bridging laboratory innovations to clinical implementation, covering safety evaluation, regulatory pathways, and translational methodologies.

Our Team Member &
Collaborator Institutions

5097f6d6-0454-4bc4-8fd9-6b6195364939.png
CUMedicine_horizontal_4C_mini.png
6f2a10d9-5b0f-409c-8713-8822a0e7ca2c.png
6d132256-46f8-49f7-9728-1fcbaae50155.png
7a8c1562-ef42-4c92-a5e8-4fa4070c27ee.png
华镁.png
Mag Med Logo.tif
b7a30e97-4fd0-46db-be5d-e77aa1e76dc0.png
24905056-7453-4d35-bc28-c7d08eb3105c.png
81273bb8-770e-4440-bc47-38ef2e2898bf.png
f54ca37f-5722-469f-9af2-657b8109b379.png
73bf0e9e-2c2f-4e79-bcfb-a4de4e0b119f.png
4c77d0f5-e852-417f-bf04-ee84030a693d.png
c2857044-9c75-40bf-9876-e4f2a8134b5b.png
b4c32160-34c7-424b-81ec-fb872d889f9d.png
678714bb-77e4-4ba5-ae1c-58e34234921e.png
c3e9031b-4459-406c-ba14-3bf2ce144af1.png
635ee06e-8594-4eae-99b6-21b8ae0d3cef.png
交通大学-红色系校徽标准版.png
中山大学-高清.png
washington-university-in-st.louis-logo.png
ec1f22b2-8ed2-4267-9b4a-568043da4c37.png
b5b213d6-a13e-4c37-b05f-d221a311cb81.png
SIAT-高清.png
北京大学-非高清.png
logo正方形_页面_1_edited.png
116365904454364062705364994_edited.jpg
logo正方形_页面_3_edited.png
logo正方形_页面_7_edited.png
logo正方形_页面_4_edited.png
logo正方形_页面_6_edited.png
图片变清晰_edited.png
logo正方形_页面_8_edited.png
logo正方形_页面_9_edited.png

Contact Us

Address: Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Hong Kong SAR

Tel. +852 3505 3308

Copyright © 2025. All Rights Reserved. RGC-AoE Centre of Aging in Musculoskeletal Degeneration and Regeneration, the Chinese University of Hong Kong.. 

bottom of page